منابع مشابه
MINI-REVIEW Cancer Stem Cells and Response to Therapy
For the past few decades, cancer stem cells (CSCs) have been the subject of intensive research. The CSC model states that cancers are organized in cellular hierarchies which explains the functional heterogeneity often seen in tumors (Harrison et al., 2010; Takebe and Ivy, 2010). Like normal tissue stem cells, CSCs are capable of self-renewal, either by symmetric or asymmetric cell division, and...
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Stem cells are cells with the ability to divide for indefinite periods and to give rise to specialized cells. Stem cell therapy has now been emerged as an extraordinary promise to treat a wide range of diseases and conditions. However, except blood stem cell transfer by bone marrow transplant which has been used as an standard practice for more than 50 years, nearly all of therapeutic potenti...
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Stem/progenitor cell based therapeutic approach in our daily routine clinical practice, has been elusive dream in medical sciences and improvement of stem cell homing as one of major challenges in cell therapy programs, has been considered a promising milestone. It has been proved that stem/progenitor cells exhibit a homing response to injured tissues/organs, mediated by interactions of chemoki...
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Gastric cancer remains a major global health threat, and most patients with advanced stage disease require chemotherapy. Resistance to therapy is a major obstacle in the management of gastric cancer, which may be due to cancer stem cells that are defined as “cancer cells within a tumor that possess the capacity for self-renewal and that can cause the heterogeneous lineage of cancer cells that c...
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Introduction: Mesenchymal stem cells (MSCs) are present in most tissues of the body. These cells are involved in various biological processes, such as maintaining tissue homeostasis and wound healing. Recent studies have shown that tumor associated MSCs (TA-MSCs) are also present in tumor microenvironment (TME) of most solid tumors. MSCs have a strong tendency to migration toward tumor tissues....
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ژورنال
عنوان ژورنال: Asian Pacific Journal of Cancer Prevention
سال: 2012
ISSN: 1513-7368
DOI: 10.7314/apjcp.2012.13.12.5947